{
  "note": "Points and displayed n count protein IDs (MMSH: unique outside homologs). Where the locus map is present, tests average transcript isoforms per physical locus; loci shared across cohorts are excluded from tests. Two-sided tests, Holm adjustment across all estimable pairs within each feature; alpha=0.05. Different letters indicate a rejected pairwise null; shared letters mean not rejected, not equivalence. n<3: no test. Exploratory comparisons do not correct for phylogenetic dependence. Reused outside homologs are counted once; matched query values are averaged per outside homolog for paired tests.",
  "tests": [
    {
      "feature": "prot_len",
      "a": "HGT",
      "b": "CORE",
      "n_a": 1,
      "n_b": 25,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "prot_len",
      "a": "HGT",
      "b": "MMSH",
      "n_a": 1,
      "n_b": 1,
      "method": "Wilcoxon signed-rank",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "prot_len",
      "a": "CORE",
      "b": "MMSH",
      "n_a": 25,
      "n_b": 1,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "cds_gc",
      "a": "HGT",
      "b": "CORE",
      "n_a": 1,
      "n_b": 25,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "cds_gc",
      "a": "HGT",
      "b": "MMSH",
      "n_a": 1,
      "n_b": 1,
      "method": "Wilcoxon signed-rank",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "cds_gc",
      "a": "CORE",
      "b": "MMSH",
      "n_a": 25,
      "n_b": 1,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "gc_skew",
      "a": "HGT",
      "b": "CORE",
      "n_a": 1,
      "n_b": 25,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "gc_skew",
      "a": "HGT",
      "b": "MMSH",
      "n_a": 1,
      "n_b": 1,
      "method": "Wilcoxon signed-rank",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "gc_skew",
      "a": "CORE",
      "b": "MMSH",
      "n_a": 25,
      "n_b": 1,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "cpg",
      "a": "HGT",
      "b": "CORE",
      "n_a": 1,
      "n_b": 25,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "cpg",
      "a": "HGT",
      "b": "MMSH",
      "n_a": 1,
      "n_b": 1,
      "method": "Wilcoxon signed-rank",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "cpg",
      "a": "CORE",
      "b": "MMSH",
      "n_a": 25,
      "n_b": 1,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "tpa",
      "a": "HGT",
      "b": "CORE",
      "n_a": 1,
      "n_b": 25,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "tpa",
      "a": "HGT",
      "b": "MMSH",
      "n_a": 1,
      "n_b": 1,
      "method": "Wilcoxon signed-rank",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "tpa",
      "a": "CORE",
      "b": "MMSH",
      "n_a": 25,
      "n_b": 1,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "rscu_dist",
      "a": "HGT",
      "b": "CORE",
      "n_a": 1,
      "n_b": 25,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "rscu_dist",
      "a": "HGT",
      "b": "MMSH",
      "n_a": 1,
      "n_b": 1,
      "method": "Wilcoxon signed-rank",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "rscu_dist",
      "a": "CORE",
      "b": "MMSH",
      "n_a": 25,
      "n_b": 1,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "pfam_n",
      "a": "HGT",
      "b": "CORE",
      "n_a": 1,
      "n_b": 25,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "pfam_n",
      "a": "HGT",
      "b": "MMSH",
      "n_a": 1,
      "n_b": 1,
      "method": "Wilcoxon signed-rank",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "pfam_n",
      "a": "CORE",
      "b": "MMSH",
      "n_a": 25,
      "n_b": 1,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "pfam_types",
      "a": "HGT",
      "b": "CORE",
      "n_a": 1,
      "n_b": 25,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "pfam_types",
      "a": "HGT",
      "b": "MMSH",
      "n_a": 1,
      "n_b": 1,
      "method": "Wilcoxon signed-rank",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "pfam_types",
      "a": "CORE",
      "b": "MMSH",
      "n_a": 25,
      "n_b": 1,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "domain_density",
      "a": "HGT",
      "b": "CORE",
      "n_a": 1,
      "n_b": 25,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "domain_density",
      "a": "HGT",
      "b": "MMSH",
      "n_a": 1,
      "n_b": 1,
      "method": "Wilcoxon signed-rank",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "domain_density",
      "a": "CORE",
      "b": "MMSH",
      "n_a": 25,
      "n_b": 1,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "intron_n",
      "a": "HGT",
      "b": "CORE",
      "n_a": 1,
      "n_b": 24,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "intron_n",
      "a": "HGT",
      "b": "MMSH",
      "n_a": 1,
      "n_b": 1,
      "method": "Wilcoxon signed-rank",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "intron_n",
      "a": "CORE",
      "b": "MMSH",
      "n_a": 24,
      "n_b": 1,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "intron_gc",
      "a": "HGT",
      "b": "CORE",
      "n_a": 1,
      "n_b": 24,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "intron_gc",
      "a": "HGT",
      "b": "MMSH",
      "n_a": 1,
      "n_b": 1,
      "method": "Wilcoxon signed-rank",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "intron_gc",
      "a": "CORE",
      "b": "MMSH",
      "n_a": 24,
      "n_b": 1,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "intron_len",
      "a": "HGT",
      "b": "CORE",
      "n_a": 1,
      "n_b": 24,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "intron_len",
      "a": "HGT",
      "b": "MMSH",
      "n_a": 1,
      "n_b": 1,
      "method": "Wilcoxon signed-rank",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "intron_len",
      "a": "CORE",
      "b": "MMSH",
      "n_a": 24,
      "n_b": 1,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "intron_ppt",
      "a": "HGT",
      "b": "CORE",
      "n_a": 1,
      "n_b": 24,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "intron_ppt",
      "a": "HGT",
      "b": "MMSH",
      "n_a": 1,
      "n_b": 1,
      "method": "Wilcoxon signed-rank",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "intron_ppt",
      "a": "CORE",
      "b": "MMSH",
      "n_a": 24,
      "n_b": 1,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "intron_bp",
      "a": "HGT",
      "b": "CORE",
      "n_a": 1,
      "n_b": 24,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "intron_bp",
      "a": "HGT",
      "b": "MMSH",
      "n_a": 1,
      "n_b": 1,
      "method": "Wilcoxon signed-rank",
      "p": null,
      "p_holm": null
    },
    {
      "feature": "intron_bp",
      "a": "CORE",
      "b": "MMSH",
      "n_a": 24,
      "n_b": 1,
      "method": "Mann-Whitney U",
      "p": null,
      "p_holm": null
    }
  ]
}